cisapride for cats megacolon
As the disease progresses cats lose the ability to defecate. No significant adverse effects have been reported in cats treated with cisapride at dosages of 011 mgkg PO 23 times daily.
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Cats with longstanding obstipation and megacolon are not likely to improve with cisapride therapy.
. Ranitidine and nizatidine H 2-receptor antagonists are reported to stimulate colonic motility by inhibiting acetylcholinesterase. The most common cause for outlet obstruction is obstruction due to poorly healed pelvic fractures which impinge on the outflow tract of the pelvis and prevent the normal passage of feces. Idiopathic megacolon is a disease in cats where the colon loses its normal motility and becomes progressively larger.
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